View Full Version : Studies of mutated protein in Lou Gehrig’s disease reveal new paths for drug discover

27th April 2011, 22:31
Hi all,

If you understand this then you can have a gold star. No star for me!

Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies in PLoS Biology, one from the University of Pennsylvania School of Medicine, and the other from colleagues at Brandeis University, both examined FUS biology in yeast and found that defects in RNA biology may be central to how FUS contributes to ALS, or Lou Gehrig's disease. These findings point to new targets for developing drugs.



28th April 2011, 15:02
If you don't understand it, I am not even going to try. Maybe someone could translate??

28th April 2011, 22:14
This article on the same subject is an easier read:


It certainly does read like a major breakthrough and seems like an effective way to monitor what might happen in a nerve cell. The question is, will it lead to anything of use? I just wish one of these alleged breakthroughs would! You sort of feel they must have enough pieces of the MND jigsaw now to make more sense of it all.


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