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  1. Thread: Doddie Weir

    by Onein300
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    573

    Yes it is a great programme. It was a...

    Yes it is a great programme. It was a chiropractor and not a physio, and yes I think it was a bit odd.

    Can you rebuild muscle? Typically not, in average als where lower motor neurones are...
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    Doug oh yes the data on plateaus and quite long...

    Doug oh yes the data on plateaus and quite long small improvements in the natural course of our disease has huge huge implications for trials.

    I will write about some of these in my final devil is...
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    My latest onein300 post ...

    My latest onein300 post

    https://onein300.com/2019/11/22/mad-as-a-hatter/
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    Hi readers. I have just published my 4th post...

    Hi readers.

    I have just published my 4th post within a series of “devil is in the detail” posts on MND Research in my onein300.com blog.

    This one is all about the calls for early access for...
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    Hi readers. It wet, it’s Monday and you all need...

    Hi readers. It wet, it’s Monday and you all need a bit of cheering up. So why bother reading my #als #mnd blog?! However, it is my regular jibberish so I hope it helps with your coffee and or...
  6. Thread: NurOwn

    by Onein300
    Replies
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    A very quick summary. Nurown is in a phase 3...

    A very quick summary.

    Nurown is in a phase 3 in the USA. It will not end until mid to late next year.

    No access is available outside of trial.

    Right to try was responded to by Brainstorm by...
  7. This is early days but this along with the biogen...

    This is early days but this along with the biogen SOD1 Trial are in my mind the key trials ongoing in the world today.

    Rock on!
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    Hi readers! I am back, onein300 with my living...

    Hi readers! I am back, onein300 with my living with #als #mnd usual fare post. A second will follow tomorrow on research for the aficionados of science and wonder. But for now, it’s just my usual...
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    Andy, The physical exercise evidence is totally...

    Andy,
    The physical exercise evidence is totally flimsy to say the least.

    Fit people definitely notice the disease earlier, as they know their bodies. Also fit people tender to not get killed by...
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    It’s my living with #mnd #als post. This week...

    It’s my living with #mnd #als post. This week pollution, watering cans, adventure, cheese and more!
    https://wp.me/p5hqWZ-2Xu
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    Andy, Sorry I misled you. I mean in your...

    Andy,

    Sorry I misled you.

    I mean in your role as a future Trustee, if elected. Nothing to do with placebo trials. Placebos are vital, end of story.

    Will you solemnly agree to be challenging...
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    Andy, I am, sadly, cynical about the biome....

    Andy,

    I am, sadly, cynical about the biome. It’s a fashion thing, leaky gut, without much solid science behind it. It’s really early days as well.
    I can see the early work just finding a mild...
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    Andy, Ok, but please tell me, will you...

    Andy,

    Ok, but please tell me, will you challenge the status quo? You need to say yes, else my vote goes elsewhere! Actually I have 5 votes!! So you have a good chance anyway!!!
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    Reduction of controls is fine as long as the...

    Reduction of controls is fine as long as the power analysis (ie significance) is strong enough.

    You need controls, despite the immediate feeling of its not fair.

    But the reality is not...
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    It’s time for my living with #mnd #als post....

    It’s time for my living with #mnd #als post. Today one of my serious research commentary posts with a “hum dinger” of a controversial title! Those affected by the disease I hope it’s a useful and...
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    It’s time for my living with #als #mnd post! With...

    It’s time for my living with #als #mnd post! With all the stress from the U.K. political scene, you need some sense to read! This week a few days away brings chaos!
    https://wp.me/p5hqWZ-2To
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    Hi everyone. It’s my living with #mnd #als blog...

    Hi everyone. It’s my living with #mnd #als blog post! Sorry about the absence.

    This week rules!! The regulation kind!

    https://wp.me/p5hqWZ-2OO
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    Morning readers! It’s my living with #mnd #als...

    Morning readers! It’s my living with #mnd #als post. This week relaxing, with a bit of history and today!
    https://wp.me/p5hqWZ-2MB
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    Morning readers. It’s my first opinion post of...

    Morning readers. It’s my first opinion post of 2019 on #mnd #als research. This is my review, kind of, of the recent MND Symposium. I take a different approach which hope you both enjoy and...
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    Hi readers. I am long overdue for a living with...

    Hi readers. I am long overdue for a living with #mnd #als post. Apologies. Here is a new one. This week, clubs...
    https://wp.me/s5hqWZ-clubs
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    Hi all. It’s my #mnd #als post! Finally after a...

    Hi all. It’s my #mnd #als post! Finally after a few weeks of absence. My usual fare. I hope to get back to a Friday lunchtime post.
    https://wp.me/p5hqWZ-2BZ

    My next post is a serious one, ie a...
  22. Thread: CuATSM ?

    by Onein300
    Replies
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    5,768

    Doug, Good stuff. I took part in one 3 years...

    Doug,

    Good stuff. I took part in one 3 years ago. It was fun. Make sure you get a copy of the scan of your brain. I asked them and they were happy to give it.

    I show it to people who think I am...
  23. Thread: CuATSM ?

    by Onein300
    Replies
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    5,768

    Just take every day as it comes. Edarvrone to me...

    Just take every day as it comes. Edarvrone to me is horrific. You have to be linked up to a drip every day for two weeks!! And then no real proven benefit! So a treatment that makes you less mobile...
  24. Thread: CuATSM ?

    by Onein300
    Replies
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    5,768

    I advise all on this forum to read the detailed...

    I advise all on this forum to read the detailed MNDA blog. It is very precise. Thank you MNDA for posting.
  25. Thread: CuATSM ?

    by Onein300
    Replies
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    5,768

    I would have to disagree on results. There has...

    I would have to disagree on results. There has been significant progress and the mnda have been instrumental in that progress. Remember MND is an extremely complex disease. But also, we are now at a...
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