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Thread: BrainStorm to start adult stem cell trial for ALS

  1. #1
    Forum Member MattJ's Avatar
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    BrainStorm to start adult stem cell trial for ALS

    Hi all,

    BrainStorm Cell Therapeutics Inc received approval from Israel's Health Ministry for a clinical trial of its adult stem cell therapy for people with amyotrophic lateral sclerosis (ALS).
    http://www.reuters.com/article/2011/...74G32020110517

    http://clinicaltrials.gov/ct2/show/N...1051882&rank=1

    Good to see this moving forward alongside the NeuralStem trial. Added bonus is the 6 month time frame.

    Matt

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    Thanks for that Matt, good news

    Sonia

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    Forum Member computatec's Avatar
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    Matt, I think you have discovered the most exciting news yet. The second link contains the real meat of the story, which is that two quite different trials will be conducted at the same time on two different groups of patients. The results will provide a massive amount of information in a short time. This is research in the fast lane.

    One part of the trial aims to find out if stem cells injected into the spinal fluid of patients can halt or reverse the disease progress. The other part of the trial aims to find out if stem cells injected directly into a muscle can halt or reverse the disease in that muscle, and the injections will be placed in 36 different places in the muscle. These trials will be carried out on a group of newly diagnosed patients and also on a group whose disease is advanced.

    Here in UK two of our own research groups have succeded in creating motor neurons from stem cells in a dish, and can keep them alive long enough to do useful research. We are also world leaders in supplying high quality clinical grade stem cell lines to any research establishment anywhere in the world. This is under the control of the UK Stem Cell Bank, see here for more infromation: http://www.ukstemcellbank.org.uk/ I was able to attend a lecture by one of the scientists a while ago.

    After a very stop and go start, stem cell technology is now going places and we will see exciting things happenning. We are living in exciting times.

    Clive
    Last edited by computatec; 19th May 2011 at 19:09.
    Living with MND. There is a solution to every problem - never ever give up.

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    Forum Member computatec's Avatar
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    A look at BrainStorm cell research

    Here is a very exciting look at new attempts to halt or reverse MND / ALS
    http://www.brainstorm-cell.com/Index...1&ArticleID=53

    If you go through the index on the left hand side of the page you can read how the technology works and what this company hopes to do with it. All is nicely explained in normal language and makes fascinating reading.

    Clive
    Living with MND. There is a solution to every problem - never ever give up.

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    Forum Member MattJ's Avatar
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    Not sure if people have seen this but an unconfirmed report from someone participating in the Phase I/II BrainStorm trial. If it is true then it's very positive news indeed:

    http://www.globes.co.il/serveen/glob...did=1000670741

    "Nevertheless, I was fortunate to be the first to get the stem cells treatment of Brainstorm Cell Therapeutics two and a half months ago (October 2010) at Hadassah hospital in Jerusalem, Israel. The procedure was simple and quick. Within 24 hours I was back home. Two and a half months later, I can testify that the Brainstorm treatment is completely safe and that my condition didn’t deteriorate in that time. In fact, not only did the disease seem to slow/stop in that time period, but preliminary follow-up tests done at Hadassah showed slight improvement in several physical functions such as breathing and speech."
    http://clinicaltrials.gov/ct2/show/N...peutics&rank=1

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    Thanks Matt, looks real interesting, fingers crossed!!

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Hi Sonia,

A light in the tunnel!

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    Yes I do hope so, I have real belief in stem cells and shall be following the links supplied by Matt with great interest.

    Sonia

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    Forum Member computatec's Avatar
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    The most interesting part of this research being carried out in Israel is the fact that the tests are on several areas all in the same trial. It is a shotgun approach so a number of answers about what works and what does not will be found very quickly.

    As far as actual treatment goes, it is likely to be very expensive. If you look under "Intellectual property" you can see that Neural stem have obtained extensive papents for the methods they have proposed.

    Clive
    Living with MND. There is a solution to every problem - never ever give up.

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    Forum Member MattJ's Avatar
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    BrainStorm readies ALS stem cell testing in U.S

    An experimental treatment developed by BrainStorm Cell Therapeutics (OTCBB:BCLI) that uses a patientís own stem cells to treat amyotrophic lateral sclerosis (ALS) is expected to begin human clinical trials in the U.S. during 2012.
    http://biotuesdays.com/2011/12/13/br...esting-in-u-s/
    Support the fight against MND: O Motor Neurone Disease Awareness Bands O

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