-
Stevedp Even if your ALT level doesn't return to normal Steve, it doesn't automatically mean stopping Riluzole.
There is quite some leeway before levels are concerning, up to 5x the upper normal level in fact (without liver impairment) and the ULN for men is 50 U/L.
This is from the SPC for Riluzole:
Riluzole should be discontinued if the ALT levels increase to 5 times the ULN. There is no experience with dose reduction or rechallenge in patients who have developed an increase of ALT to 5 times ULN. Readministration of riluzole to patients in this situation cannot be recommended.
Leave a comment:
-
Hi Steve. Mine went up to 58 and went down. I had that happen twice. Apparently its common until you've been on it sometime.
You neurologist should guide you on it.
ILeave a comment:
-
Riluzole and ALT serum levels
So second blood test and my alt serum level has gone up from 31 to 73, which is abnormal will this go back down? Am feeling a lot more tired hopefully will get me energy back up soon.
- Welcome to the MND Association Forum.
If this is your first visit, be sure to check out the Forum Guidelines. You will need to Register before you can post. All registrations are manually approved by the Forum Admin team to try and help prevent spam so there may be a slight delay between registering and being able to post.
To start viewing posts, select the section of the forum that you want to visit from the selection below.
Leave a comment: