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    Review of genetics

    This is a master of reviewers reviewing the genetic position.....

    With thanks to Lee Millard on Twitter pointing this out

    https://www.sciencedirect.com/scienc...69996120304319
    Warmly


    Andy

    ​Diagnosed 03/2015. One sided limb onset (arm) sporadic ALS/MND. MND hitting - now 50% left arm and 90% right arm, plus other bits including left shoulder

    "Things turn out the best for people who make the best of the way things turn out"

    #2
    Thanks for passing this on Andy.

    Doug

    Comment


      #3
      Yes thanks andy

      Comment


        #4
        Thnkyou for posting Andy

        Comment


          #5
          Andy,

          Which is the MNDA's preferred treatment currently in Phase 3?
          Copyright Graham

          Comment


            #6
            Received some really good news today. Stephens als is not genetic. Thank goodness.

            Comment


              #7
              Good morning Graham,

              As far as I know, there is nothing in phase 3.

              The one I'm vaguely keeping my eye on is Nurown (sorry I'm not sure that's the right spelling) which is some sort of nostrum that is injected into the spine and has caused a number of people in the US phase 3 trial to reverse symptoms and that reversal has now reversed back given the trial has ended while the drug company tries to get some money to invest in producing the thing.

              Of course, the US is a bit of a minefield at the moment given the vast amount of money being ploughed into Covid treatments and seemingly taking money away, at least investment money, from things that deal with stuff like MND
              Warmly


              Andy

              ​Diagnosed 03/2015. One sided limb onset (arm) sporadic ALS/MND. MND hitting - now 50% left arm and 90% right arm, plus other bits including left shoulder

              "Things turn out the best for people who make the best of the way things turn out"

              Comment


                #8
                Originally posted by nunhead_man View Post
                Good morning Graham,

                As far as I know, there is nothing in phase 3.

                The one I'm vaguely keeping my eye on is Nurown (sorry I'm not sure that's the right spelling) which is some sort of nostrum that is injected into the spine and has caused a number of people in the US phase 3 trial to reverse symptoms and that reversal has now reversed back given the trial has ended while the drug company tries to get some money to invest in producing the thing.

                Of course, the US is a bit of a minefield at the moment given the vast amount of money being ploughed into Covid treatments and seemingly taking money away, at least investment money, from things that deal with stuff like MND
                Hi Andy,

                posted today https://ir.brainstorm-cell.com/2020-...se-3-ALS-Study
                I’m going to do this even if it kills me!

                Comment


                  #9
                  Following on from Barry's post:

                  I listened into the Brainstorm press conference re NurOwn's Phase III results, quite interesting. A recording is available for a short period of time https://www.webcaster4.com/Webcast/Page/2354/38723

                  If you need a passcode, it's 38723

                  I see their share price dived...
                  ​Diagnosed 03/2007. Sporadic Definite ALS/MND Spinal (hand) Onset.
                  Eye gaze user - No functional limbs - No speech - Feeding tube - Overnight NIV.

                  Comment


                    #10
                    Thank you Andy, much appreciated.

                    The fact that the Brainstorm share price fell by 67 percent today sums up the reality that the Brainstorm trial failed. Very sad and disappointing. However, BCLI's net capitalisation despite the drop is $125M, more than twice in 2014, so the company will carry on.

                    There are more phase 3 trials Andy but I'm not sure what they are. I think the antisense trials offer hope too.
                    Copyright Graham

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