ALS TDI Summit Friday 5th November.

[LindaB]

I listened in for the 1st hour and will look forward to the recording for the rest. Much of the terminology new to me too...but fascinating. My biggest take home, even from that hour, was how determined and driven the scientists involved are! Devoted to finding better treatments for slowing down...stopping...reversing ALS/MND...
We live in hope🙏✊🏻👍🏻

[Rosemary6NT]

Ellie in the early part of this year I was very keen on researching everything but as the reality started to kick in I dropped the research and started a painting course online which took all my focus. From a completely detached standpoint it is the most fascinating problem untangling the cause/causes of the various MND’s but so much to read and learn and try to make sense of! My DNA analysis shows that none of the common genetic causes are there. Interestingly (to me, sorry this is all about me 🙄) I read that amongst the “high risk” occupations are agriculture and construction/carpentry. It so happens that the first 18years of my working life were spent in agricultural research as a biochemist until I went off the tracks a bit and became a full time craft woodturner which I only retired from as I became physically incapable of continuing. Coincidence? Anyhoo, I’ve started back with a little bit of research now and again when I’m in the mood. Sorry for waffling.

[Rosemary6NT]

Sorry I won't be able to attend I'm too busy watching paint dry 😉😁👀😍xx

😂😂😂

[Ellie]

I read that amongst the “high risk” occupations are agriculture and construction/carpentry. It so happens that the first 18years of my working life were spent in agricultural research as a biochemist until I went off the tracks a bit and became a full time craft woodturner which I only retired from as I became physically incapable of continuing. Coincidence?

The general consensus is that a multistep process requiring six distinct steps leads to the onset of sporadic ALS. These six exposures are both genetic and environmental, and the final one is the onset trigger, so we basically had 5 chances to dodge the ALS bullet, but didn’t…

That requires a special amount of (bad) luck, eh xx

[matthew55]

If it wasn't for bad luck I'd have no luck at all. 😉😅😘😍xx

[Rosemary6NT]

Ellie that's interesting. Now you've done all the hard work researching are there any digestible references you can point me to? xx

[Ellie]

Rosemary6NT I found this paper on the multistep process.

It is very detailed but you can skip sections, the stats and maths if that's not your thing, without losing significant context. Give it a go. xx

[Rosemary6NT]

Ellie Thanks Ellie, that's great, I will look at it later xx