ALS News

[Lynne K]

https://alsnewstoday.com/2019/04/11/...aign=OneSignal


Very interesting report. I think worthy of more research. Lynne

[Doug Carpenter]

Many thanks for the link Lynne. As you say, an interesting – certainly very thorough – piece of research.

I mentioned recently the C9orf72 study that I and John Burton are involved in and I’m coming to the view that progress towards at least a partial treatment – though not a cure – may come quicker for familial MND than sporadic MND.

At least the C9orf72 hexanucleotide repeat and the NMD pathway suggests specific targets for further research. But we need to remember there’s a long road from fruit flies and mouse models to human patients.

I can’t remember if I’ve posted this link before:

https://link.springer.com/content/pd...018-8983-8.pdf

but it’s to a recent paper that I think summarizes very well the present state of knowledge about MND, especially the gene-mediated forms. I’m slightly biased because it’s by the team at the Nuffield Department for Clinical Neuroscience at the John Radcliffe, who look after me so expertly.

Still a long way to go!

Doug

[johnburton]

Hi Doug,
I'll be going to the FaTHoM event in Oxford on Tuesday, with my siblings. Will you be there?
John

[Lynne K]

Here's another very interesting piece of research news. Lynne

https://alsnewstoday.com/2019/04/15/...tm_campaign=On

[Lynne K]

Thanks for the link Doug. I've saved it to read later as we're busy, busy. Lynne

[Dis1960]

Another link from ALS News :

https://alsnewstoday.com/2019/04/30/...CPDqlTmIgR1CDg

[Doug Carpenter]

Thanks Dis1960.

That looks like a seriously good piece of research! It helps to shed light on how these pesky proteins accumulate.

Doug